How B Vitamins Could Slow Cognitive Decline and Protect Against Dementia

How B Vitamins Might Protect Your Brain as You Age

Emerging research suggests that the family of B vitamins — especially vitamin B12 and folate (B9) — play an important role in brain health and may help slow cognitive decline and reduce the risk of dementia as we get older — long before symptoms appear. SciTechDaily

B vitamins work together in a set of chemical pathways called one-carbon metabolism, which supports critical cellular functions like DNA synthesis and amino acid processing. Because multiple B vitamins must act together to support these processes, it’s difficult to study them in isolation. But this teamwork is also what makes the B complex so vital to health. SciTechDaily

One of the most well-studied nutrients in this group is vitamin B12, which becomes harder for many people to absorb from food as they enter their 70s and 80s. When B12 absorption declines, nerve health — including that of brain and spinal cord cells — may be affected, increasing the risk of cognitive decline and dementia. SciTechDaily

Experts also emphasize that traditional blood tests may not always detect functional B12 deficiency because they measure total B12 rather than the portion the body can actually use. Tests that measure methylmalonic acid and homocysteine can offer a more accurate picture of deficiency and associated dementia risk. SciTechDaily

Importantly, researchers note that vascular health — the health of the brain’s blood vessels — plays a major role in cognitive decline and dementia. B vitamin deficiencies are linked to elevated homocysteine levels, which are associated with vascular problems that may contribute to dementia more often than the classic protein accumulations seen in Alzheimer’s disease. SciTechDaily

Because some forms of cognitive decline may be connected to nutritional deficiencies rather than irreversible brain damage, identifying and correcting deficiencies early on may offer a simple, affordable way to slow cognitive deterioration. While more research is needed, the evidence points to checking B vitamin status — particularly B12 and folate — as part of a broader strategy for long-term brain health. SciTechDaily

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Source:
https://scitechdaily.com/how-b-vitamins-could-slow-cognitive-decline-and-protect-against-dementia/